NCT04841018

Does Low Dose of Dexamethasone Enhance Analgesic Quality of Caudal Analgesia in Children Undergoing Orchiopexy?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 273 (actual)
• Sponsor: Yonsei University · Academic / Other
• Sex: Male
• Age: 6 Months – 6 Years
• Healthy volunteers: Accepted

Summary

Caudal block is one of the most effective modalities to reduce pain both during and after the surgery involving areas under the umbilicus. According to previous research, 0.5mg/kg-1.5mg/kg dexamethasone is known to enhance the analgesic quality of caudal block in children. Despite the fact that this high dose of dexamethasone is used to treat airway edema in actual practice and no adverse side effect related to dosage has been reported, it is 3 to 15 times higher than the daily antiemetic dose of dexamethasone that is used in standard care of anesthesia. Therefore, our study aims to assess the effect of the more practical, antiemetic dose of dexamethasone (0.15mg/kg) as an adjuvant to enhance the quality of caudal block through a non-inferiority trial.

Conditions

• Patients With Cryptorchism Who Are Planning to Undergo Orchiopexy

Interventions

Type	Name	Description
DRUG	High dose dexamethasone	After caudal block with 1.2ml/kg of 0.15% ropivacaine, the patient receives 0.5mg/kg of intravenous dexamethasone
DRUG	Low dose dexamethasone	After caudal block with 1.2ml/kg of 0.15% ropivacaine, the patient receives 0.15mg/kg of intravenous dexamethasone

Timeline

• Start date: 2021-03-24
• Primary completion: 2023-08-29
• Completion: 2023-09-01
• First posted: 2021-04-12
• Last updated: 2023-09-14

Locations

1 site across 1 country: South Korea