Trials / Active Not Recruiting
Active Not RecruitingNCT04840511
The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular Trapping
The Effect of Perioperative Lidocaine Infusion on Neutrophil Extracellular Trapping in the Patients Undergoing the Robot-assisted Prostatectomy
- Status
- Active Not Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- The Catholic University of Korea · Academic / Other
- Sex
- Male
- Age
- 20 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
This study will be done to investigate perioperative lidocaine infusion on neutrophil extracellular trapping in the patients undergoing the robot-assisted prostatectomy.
Detailed description
Neutrophil extracellular trapping by analyzing the meyloperoxidase, neutrophil elastase, citrullinated histone3
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | lidocaine group | lidocaine 1.5 mg/kg bolus (infused over 10 min) followed by 2.0 mg/kg/h during operation and 1.0 mg/kg/h during postoperative 24 hours (no more than 120 mg/h) |
| DRUG | control group | normal saline 0.15 ml bolus followed by 0.2 ml/kg/hr during operation and 0.1 ml/kg/hr during postoperative 24 hours |
Timeline
- Start date
- 2021-09-27
- Primary completion
- 2022-04-30
- Completion
- 2027-04-30
- First posted
- 2021-04-12
- Last updated
- 2023-01-13
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT04840511. Inclusion in this directory is not an endorsement.