NCT04838535

Follicular Fluid Raman Shifts and IVF Outcomes

The Correlation Between Follicular Fluid Raman Spectrum and Embryo Development in Infertile Patients With Polycystic Ovary Syndrome

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: ShangHai Ji Ai Genetics & IVF Institute · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

This study intends to collect about 150 cases of follicular fluid samples from PCOS and non-PCOS infertility patients undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles (in clinical routines).We tend to detect Raman metabolic profile of the follicular fluid of the PCOS and non-PCOS groups, and find the correlation between the metabolic profile of the follicular fluid of PCOS patients and the oocyte quality, IVF outcome and subsequent embryo development are also under investigation. Metabolomics analysis was applied to look for markers of follicular fluid in PCOS patients, and further exploring data and strategies to improve the embryonic development potential and IVF outcome of PCOS patients.

Conditions

• Polycystic Ovary Syndrome
• IVF

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Raman spectrum	The wavelength of the follicular fluids were scaned by Raman spectrum

Timeline

• Start date: 2019-06-19
• Primary completion: 2021-06-19
• Completion: 2021-12-19
• First posted: 2021-04-09
• Last updated: 2021-04-09

Locations

1 site across 1 country: China