NCT04838418

Transorbital Ultrasound and Other Markers for Prognosis Prediction After Cardiac Arrest

Transorbital Ultrasound and Other Markers for Prognosis Prediction After Cardiac Arrest (TOMCAT)

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 80 (estimated)
• Sponsor: University Hospital Pilsen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In sudden cardiac arrest patients with return of spontaneous circulation, brain damage is one of the main determinants of short-term mortality and poor prognosis (CPC 3-5). It is important to properly select group of patients in whom treatment is futile. According to current guidelines, multimodal approach is recommended. Optic nerve sheath diameter measured by ultrasound is non-invasive, fast, low-cost and readily available bed-side method, but evidence for its use as neuroprognostication modality is limited to only few small studies. The aim of this study is to evaluate validity of ONSD as neuroprognostication method at larger cohort of patients, compare it with other established methods and compare ultrasound and CT measurement of ONSD.

Detailed description

Additional relevant MeSH terms: cardiac arrest, cardiovascular diseases, optic nerve sheath diameter.

Conditions

• Cardiac Arrest

Interventions

Type	Name	Description
PROCEDURE	Optic nerve sheath diameter measured by transorbital ultrasound	Optic nerve sheath diameter measured 3 mm behind eyeball. For every eyeball 2 measurements in axial and 2 measurements in sagital projections are performed. Summary value for every eyeball is arithmetic mean from these 4 measurements.

Timeline

• Start date: 2021-01-04
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2021-04-09
• Last updated: 2026-04-09

Locations

1 site across 1 country: Czechia