NCT04838093

COVID-19 Testing in Patients With Vascular Disorders

COVID-19 Testing in Patients With Vascular Disorders - a Prospective Cohort Study at a Tertiary Care Hospital

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 2,243 (actual)
• Sponsor: Medical University of Vienna · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

Background: To investigate the prevalence of SARS-CoV-2 infection in hospitalized patients with vascular disorders after implementing institutional and governmental safety measures. Materials and Methods: Vascular patients (VPs) admitted to our tertiary care hospital were routinely tested for SARS-CoV-2 infection on a two days basis between March and December, 2020. The prevalence of SARS-CoV-2 was compared between VPs and two independent Austrian populations (April and November 2020) tested by the Austrian Ministry of Science. The results were also compared to a cohort of health care personnel (HCP) working in close proximity to the study patients, tested weekly, between March and December, 2020. RT-PCR and antigen test were used to detect SARS-CoV-2.

Conditions

• Covid19

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	PCR	Nasal or pharyngeal respiratory swabs were routinely taken of each patient admitted at our departments and repeated regularly at 48 h intervals during the inpatient stay. In the HCP cohort testing for SARS-CoV-2 RNA was performed, on a weekly basis, at the Department of Laboratory Medicine, Medical University of Vienna, Austria, using real-time polymerase chain reaction (RT-PCR). Comparability of the results of all test methods used was confirmed by participation in international quality control ring trials.

Timeline

• Start date: 2020-03-01
• Primary completion: 2020-12-01
• Completion: 2021-01-01
• First posted: 2021-04-08
• Last updated: 2021-04-08

Locations

1 site across 1 country: Austria