Trials / Completed
CompletedNCT04835675
AssesSment of Early-deteCtion basEd oN liquiD Biopsy in Hepatobiliary Cancer Malignancies
Development and Validation of the Performance of a cfDNA Methylation-based Model Combined With Serum Tumor Markers for Early Hepatobiliary Malignancies Detection
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 496 (actual)
- Sponsor
- Zhujiang Hospital · Academic / Other
- Sex
- All
- Age
- 40 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
This study is a prospective, multicenter study aimed to develop and validate the performance of combined assays for cfDNA methylation markers and serum tumor markers in early hepatobiliary malignancies detection. Circulating tumor DNA (ctDNA) mutation, blood RNA markers and tissue will also be evaluated. The study will enroll approximately 496 participants, including participants with malignant or benign diseases of the hepatobiliary system.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | Multi-cancer early detection test | Blood collection and multi-cancer early detection testing |
Timeline
- Start date
- 2021-03-12
- Primary completion
- 2022-03-31
- Completion
- 2022-06-30
- First posted
- 2021-04-08
- Last updated
- 2023-03-02
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04835675. Inclusion in this directory is not an endorsement.