NCT04835545

Work of Breathing Under Extreme Hypercapnia Induced by Ventilation Insufficiency

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Czech Technical University in Prague · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to investigate Work of Breathing of a person in simulated avalanche snow and consequent use of the measured data for judging which one of three simulated scenarios are alike while increasing hypercapnia in the simulated avalanche snow.

Detailed description

The study is a part of a university diploma thesis aimed at studying physiological conditions and development of breathing parameters of a person breathing in the simulated avalanche snow. The Investigator is measuring Work of Breathing in three scenarios: a) 2L air pocket, b) 2L air pocket with resistance compensation and c) no air pocket. The investigator hypothesize that the Work of Breathing during compensation of air pocket will be alike with no air pocket scenario, thus proving significance of the resistance reduction for survival. The aim of the study is to investigate the effect of Work of Breathing on gas exchange in subjects breathing into the simulated avalanche snow scenarios.

Conditions

• Accident Caused by Snow Avalanche

Interventions

Type	Name	Description
OTHER	extreme hypercapnia induced by ventilation insufficiency	extreme hypercapnia

Timeline

• Start date: 2021-03-29
• Primary completion: 2024-04-01
• Completion: 2024-04-01
• First posted: 2021-04-08
• Last updated: 2022-07-22

Locations

1 site across 1 country: Czechia