NCT04834414

CHIlled Platelet Study "CHIPS"

CHIlled Platelet Study

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 1,000 (actual)
• Sponsor: Philip Spinella · Academic / Other
• Sex: All
• Age: 0 Days – 84 Years
• Healthy volunteers: Not accepted

Summary

A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the transfusion of cold stored platelets to standard room temperature stored platelets. The primary objective is to establish that cold stored platelets have a non-inferiority (or superiority) to room temperature platelets.

Conditions

• Acute Blood Loss

Interventions

Type	Name	Description
BIOLOGICAL	Cold Stored Platelets	Platelets stored at 1-6 degree Celsius
BIOLOGICAL	Room Temperature Platelets	Platelets stored at 20-24 degrees Celsius

Timeline

• Start date: 2021-10-21
• Primary completion: 2025-03-25
• Completion: 2025-04-21
• First posted: 2021-04-08
• Last updated: 2025-07-11

Locations

27 sites across 2 countries: United States, Australia

Regulatory

• FDA-regulated drug study