NCT04833647

Influence of Prematurity and Its Respiratory Sequel on Exercise Testing in Childhood

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 83 (actual)
• Sponsor: Rambam Health Care Campus · Academic / Other
• Sex: All
• Age: 7 Years – 10 Years
• Healthy volunteers: Accepted

Summary

Prospective study comparing hemodynamic and respiratory changes and exercise capacity during Cardio-Pulmonary-Exercise-Testing (CPET) in 4 groups of infants; Three different groups of premature infants and term controls

Detailed description

The study population included 4 groups of infants; preterm infants born \< 300 weeks' gestation with BPD (i.e. oxygen dependence for at least 28 postnatal days 5), preterm infants born \< 300 weeks' gestation without BPD, late preterm infants (born at 340-366 weeks' gestation) and term controls. Pulmonary function testing and spirometry were measured Participants performed CPET on an electronically braked cycle ergometer. During the exercise testing, serial saturation, heart rate and blood pressure measurements were obtained. The peak oxygen consumption (VO2max) was measured and served as the primary endpoint of the study.

Conditions

• The Peak Oxygen Consumption (VO2max) Was Measured and Served as the Primary Endpoint of the Study

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cardio-Pulmonary-Exercise-Testing (CPET)	Cardio-Pulmonary-Exercise-Testing (CPET) . During the exercise testing, serial saturation, heart rate and blood pressure measurements were obtained. The peak oxygen consumption (VO2max) was measured and served as the primary endpoint of the study

Timeline

• Start date: 2016-04-01
• Primary completion: 2020-08-01
• Completion: 2021-02-01
• First posted: 2021-04-06
• Last updated: 2021-04-09