NCT04833296

Ropivacaine Use in Interscalene Block; What is the Minimal Effective Analgesic Concentration (MEAC 90)

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: Healthpoint Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aim to calculate the minimal effective ropivacaine concentration required achieve successful analgesic interscalene block in 90% of patients (MEAC90)

Detailed description

* Before induction of general anesthesia, all patients will receive interscalene block using 15ml of ropivacaine which concentration will be based on the response of the previous patient. * Based on biased-coin design up-down sequential method: if patient has pain free recovery, a successful block, the next patient will be randomized to receive either the same ropivacaine concentration or a concentration 0.01% w/v less. However, if he has an unsuccessful block, the next patient will receive a concentration 0.01% w/v higher. * Patients with pain free recovery will be considered to have positive response. * Patients' responses will be analyzed to calculate the MEAC90.

Conditions

• Postoperative Pain

Interventions

Type	Name	Description
DRUG	Ropivacaine	all patients will receive interscalene block using same volume of ropivacaine but in different concentrations

Timeline

• Start date: 2021-05-01
• Primary completion: 2021-09-30
• Completion: 2021-09-30
• First posted: 2021-04-06
• Last updated: 2021-04-06

Locations

1 site across 1 country: United Arab Emirates