NCT04832672

Sequence of Radiation and Targeted Therapy in Brain Metastases

The Optimal Sequence of Intracranial Radiotherapy Compared to Systematic Tyrosine Kinase Inhibitors for Gene-driven Brain Metastases in Targeted Treatment Era

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 570 (actual)
• Sponsor: Chinese Academy of Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The investigators conducted a single institutional, retrospective cohort study to demonstrate the appropriate treatment strategy of upfront intracranial radiotherapy or upfront targeted therapy in patients with brain metastases, including an assessment of its feasibility and toxicity.

Conditions

• The Optimal Sequence of Radiotherapy and Systematic Tyrosine Kinase Inhibitors in Treating Brain Metastases

Timeline

• Start date: 2010-10-01
• Primary completion: 2021-03-01
• Completion: 2021-03-01
• First posted: 2021-04-06
• Last updated: 2021-04-06

Locations

1 site across 1 country: China