NCT04831827

Promoting Equity for Cancer Screening and Follow-up

Promoting Equity Through Multicomponent Strategies for Cancer Screening and Follow-up (PREMiS)

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 50 Years – 75 Years
• Healthy volunteers: Accepted

Summary

This is a randomized trial to assess the efficacy of reminder mechanisms on colorectal cancer (CRC) screening uptake among a cohort of patients who were previously mailed a multitarget stool DNA (mt-sDNA) test and did not complete the screening. Patients will be identified as being due for CRC screening and will be mailed a mt-sDNA kit to their home. Patients who do not complete screening with mt-sDNA within 30 days will be identified and randomized into one of three study arms to receive reminders to complete the mt-sDNA screening. The primary outcome is the rate of completion of screening for colorectal cancer with mt-sDNA test.

Detailed description

Colorectal cancer (CRC) is the third leading cause of cancer-related death in the United States, and screening has been shown to reduce mortality from CRC. Screening is underutilized in the United States, particularly in some communities such as Blacks/African Americans, American Indians/Alaskan Natives, and rural populations, contributing to disparities in mortality. For CRC screening, mt-sDNA testing is one of several tests that are recommended by the United States Preventive Services Task Force (USPSTF). As part of a quality improvement program at our institution, those who are due for CRC screening are identified using a validated electronic algorithm and a kit is mailed directly to each patient. Our intervention is initiated on non-respondents to the mailed mt-sDNA outreach by testing the use of a technology-enabled reminder system. Thirty days after being mailed a mt-sDNA kit, patients who have not completed the screening will be randomized to receive a reminder to complete the mt-sDNA screening by one of three mechanisms (time 0): 1. Automated reminder using the EHR patient portal messaging system. 2. Automated reminder using a customized interactive voice response (IVR) system 3. Personalized reminder phone calls from the clinical team This will allow for an empirical test of processes that can be employed to improve delivery of CRC screening and reduce preventable deaths in populations that are underserved with evidence-based interventions.

Conditions

• Colorectal (Colon or Rectal) Cancer

Interventions

Type	Name	Description
OTHER	IVR Reminder	Participants will receive an interactive voice reminder (IVR) to complete mt-sDNA screening at day 7 and 21.
OTHER	Phone call from research team	Patients will receive a scripted phone call from the research team to remind them to complete the mt-sDNA screening at day 7 and 21.
OTHER	EHR Portal message	Patients will receive an EHR patient portal message with a scripted message to remind them to complete the mt-sDNA screening at day 7 and 21.

Timeline

• Start date: 2021-09-01
• Primary completion: 2023-05-01
• Completion: 2023-05-01
• First posted: 2021-04-05
• Last updated: 2021-10-27

Locations

1 site across 1 country: United States