NCT04831073

European Registry of Type A Aortic Dissection

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,902 (actual)
• Sponsor: Helsinki University Central Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Acute Stanford type A aortic dissection (TAAD) is a life-threatening condition. Surgery is usually performed as a salvage procedure and is associated with significant postoperative early mortality and morbidity. Understanding the patient's conditions and treatment strategies which are associated with these adverse events is essential for an appropriate management of acute TAAD.

Detailed description

Twenty centers from eight European centers of cardiac surgery have collaborated to create a multicentre observational registry (ERTAAD), which will enroll consecutive patients who underwent surgery for acute TAAD from January 2005 to March 2021. The investigators will compare patient's comorbidities, condition at referral, surgical strategies and perioperative treatments in patients with and without early and late adverse events. The primary clinical outcome will be in-hospital mortality, late mortality and reoperations on the aorta. Secondary outcomes will be stroke, acute kidney injury, surgical site infection, reoperation for bleeding, transfusion of blood products and length of stay in the intensive care unit.

Conditions

• Type A Aortic Dissection

Interventions

Type	Name	Description
PROCEDURE	Surgery on the ascending aorta with or without repair of the aortic root and/or aortic arch	Surgical repair of the ascending aorta with or without surgical repair of the aortic root and/or aortic arch

Timeline

• Start date: 2023-02-28
• Primary completion: 2024-12-06
• Completion: 2024-12-06
• First posted: 2021-04-05
• Last updated: 2024-12-11

Locations

20 sites across 8 countries: Belgium, Czechia, Finland, France, Germany, Italy, Spain, United Kingdom