NCT04831047

The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Eyelid Position, Eye Redness, and Eye Appearance

The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Palpebral Fissure Height, Eye Redness, and Patient-reported Eye Appearance

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 114 (actual)
• Sponsor: University of Miami · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of the research is to see if Upneeq ( oxymetazoline 0.1% ophthalmic solution) has an effect on eyelid position, eye redness, or patient-perceived appearance of the eyes.

Conditions

• Ptosis, Eyelid
• Conjunctiva Inflamed
• Eye Manifestations

Interventions

Type	Name	Description
DRUG	Oxymetazoline hydrochloride 0.1% ophthalmic solution	One drop of Upneeq (Oxymetazoline hydrochloride 0.1% ophthalmic solution) will be applied to the ocular surface of each eye.
DRUG	Placebo	One drop of placebo (balanced saline solution) will be applied to the ocular surface of each eye.

Timeline

• Start date: 2021-06-08
• Primary completion: 2022-04-01
• Completion: 2022-04-01
• First posted: 2021-04-05
• Last updated: 2023-04-24
• Results posted: 2023-04-24

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study