NCT04827446

Lighting Intervention for Cancer-related Fatigue

A Randomized Trial Of The SYNC APP

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 139 (actual)
• Sponsor: University of Michigan Rogel Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Fatigue is a major problem for cancer patients, and one that can persist long after treatment ends. Recent work has demonstrated that light therapy may mitigate or reduce fatigue levels in both cancer patients and cancer survivors. This protocol seeks to assess how lighting interventions distributed through a mobile app affect fatigue, sleep, and quality of life across three populations of cancer patients: breast cancer and prostate cancer, and patients who have undergone autologous hematopoietic stem cell transplant (HSCT). Participants will be randomized 1:1 to either the interventional SYNC app or to a control app.

Conditions

• Breast Cancer
• Prostate Cancer
• Hematologic Malignancy
• Survivorship
• Fatigue

Interventions

Type	Name	Description
OTHER	Wearable Sensor	Patient is given a wearable device to wear for 12 weeks.
OTHER	Blue-blocking glasses	Patient is given blue-blocking glasses to wear at instructed times.
OTHER	Clear glasses	Patient is given glasses that block no visible light.
OTHER	Full SYNC app	Patient downloads the SYNC app and is given light interventions designed to have a targeted, personalized effect on the circadian clock.
OTHER	"Dummy" SYNC app	Patient downloads the SYNC app and is given light interventions designed to have minimal impact on the circadian clock.

Timeline

• Start date: 2021-07-15
• Primary completion: 2023-03-09
• Completion: 2023-03-09
• First posted: 2021-04-01
• Last updated: 2025-07-09
• Results posted: 2025-07-09

Locations

1 site across 1 country: United States