NCT04827316

Clinical Utility and Outcome Prediction of Cardiovascular Computed Tomography (PREDICT-CT)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 4,200 (estimated)
• Sponsor: Insel Gruppe AG, University Hospital Bern · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In this study the investigators retrospectively and prospectively collect information from enrolled subjects undergoing CCTA and evaluate the association of cardiac and non-cardiac imaging with laboratory markers and clinical data including outcome.

Detailed description

In this study the investigators retrospectively and prospectively collect information from enrolled subjects through a period of a total of 10 years to evaluate multidimensional associations between phenotypic manifestations of cardiovascular disease via CCTA and cardiac and non-cardiac imaging, serum biomarkers, demographic and clinical information, clinical presentation (cross-sectional), therapy changes (time-varying) and their ability to predict mortality and MACE (major adverse cardiac event ) (longitudinal) in patients clinically indicated for CCTA. The aim is to establish a comprehensive cross-sectional, time-varying and longitudinal data collection for individuals undergoing clinically-indicated CCTA to date in order to apply novel multiparametric approaches to determine cardiovascular significance to clinically-important patient-centered events. For data collection this registry will follow a standard CRF (case report form) structure, so to enable the merging of this data-set with other international registries, which might contribute in overcoming some gaps of knowledge from previous CCTA studies.

Conditions

• Coronary Artery Disease
• Coronary Arteriosclerosis
• Coronary; Ischemic

Timeline

• Start date: 2017-06-01
• Primary completion: 2031-02-01
• Completion: 2031-02-01
• First posted: 2021-04-01
• Last updated: 2024-10-18

Locations

1 site across 1 country: Switzerland