NCT04826081

Study on the Risks of Symptomatic Dengue on Pregnancy

Prospective Study on the Risks of Symptomatic Dengue on Pregnancy

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 336 (estimated)
• Sponsor: Centre Hospitalier Universitaire de la Réunion · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Dengue fever is the most common arbovirus worldwide (390 million people infected per year) and is a global public health problem. This public health problem is also becoming European due to its rapid expansion over the past decade with an increase in cases of 400% and the appearance of the first indigenous cases of dengue in Europe. Studies on the consequences of dengue fever on pregnancy find contradictory results. In fact, most of these studies are observational studies describing the risk of dengue fever for pregnancy, without comparison with a control group or comparing the different pregnancy morbidities to those found during pregnancy in the general population. Other research is retrospective case-control studies with major biases in the definitions of obstetric complications, which makes the results questionable. The study therefore proposes to carry out a prospective case-control study with rigorous matching criteria, strict definitions of cases, controls and obstetric complications.

Conditions

• Dengue
• Pregnancy

Interventions

Type	Name	Description
OTHER	data collection	data collection

Timeline

• Start date: 2021-06-15
• Primary completion: 2024-01-01
• Completion: 2024-03-01
• First posted: 2021-04-01
• Last updated: 2021-11-04

Locations

1 site across 1 country: France