NCT04826042

Effect of Contrast Medium on Optic Nerve Sheath Diameter

: Effect of Epidural Injection of Normal Saline or Contrast Medium on Optic Nerve Sheath Diameter

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: Keimyung University Dongsan Medical Center · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

One method of indirect measurement of intracranial pressure is using optic nerve sheath diameter. There is no study whether equal volume of contrast medium injection has any increasing effect of optic nerve sheath diameter. This study is designed to measure the changes of optic nerve sheath diameter and cerebral oxygenation when equal volume of contrast medium or normal saline was injected in epidural space.

Detailed description

Previous study showed that different volume of injections (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia showed siginifiant increase of optic nerve sheath diameter in group of high volumes. Increase of ICP can result in harmful effect including reduced cerebral flow and oxygen saturation. Also, increase of ICP can cause headache, syncope and transient loss of visual acuity. The proven and valid method of measuring ICP indirectly is using optic nerve sheath diameter. This study was designed to examine the changes of optic nerve sheath diameter and cerebral oxygenation when equal volume of contrast medium or normal saline was injected in epidural space.

Conditions

• Optic Nerve Sheath Diameter

Interventions

Type	Name	Description
OTHER	thoracic epidural catheterization	thoracic epidural catheterization

Timeline

• Start date: 2021-03-29
• Primary completion: 2022-08-29
• Completion: 2022-08-29
• First posted: 2021-04-01
• Last updated: 2022-12-20

Locations

1 site across 1 country: South Korea