NCT04825548

Post-thrombotic Syndrome After Deep Venous Thrombosis (DVT) in Patients Treated According to the NOPHO ALL2008 Protocol

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 27 (actual)
• Sponsor: Aarhus University Hospital · Academic / Other
• Sex: All
• Age: 1 Year
• Healthy volunteers: Accepted

Summary

Acute lymphoblastic leukemia (ALL) is the most common malignant disease in childhood. Today more than 90% of children and 75% of adults (18-45 years) survive ALL. The enzyme Asparaginase (Asp) is an indispensable part of the multiagent treatment of ALL. Treatment related severe acute toxicities are common. Especially in teenagers and adults, thromboembolism is one of the most common acute toxicities and may result in post thrombotic syndrome (PTS) or pulmonary hypertension. The knowledge about these late effects is limited, including for ALL patients.

Conditions

• Acute Lymphoblastic Leukemia
• Post Thrombotic Syndrome

Interventions

Type	Name	Description
OTHER	No intervention	Examination of patients with previous DVT

Timeline

• Start date: 2020-07-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2021-04-01
• Last updated: 2024-02-06

Locations

1 site across 1 country: Denmark