NCT04825158

Study of the Role of Hemostasis in Perioperative Anaphylaxis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 30 (estimated)
• Sponsor: University Hospital, Strasbourg, France · Academic / Other
• Sex: All
• Age: 2 Years
• Healthy volunteers: Not accepted

Summary

Anaphylaxis is a severe and life-threatening complication during the perioperative period. Perioperative anaphylaxis is still associated with a significant mortality despite quick and efficient management using epinephrine, the mainstay of acute treatment. Experimental data and few case reports are suggesting that hemostasis, and more precisely platelets, could play a role in anaphylaxis. Our main hypothesis is that activation of the hemostatic system contributes to the severity of the reaction

Conditions

• Hemoptysis
• Perioperative Complication
• Anaphylaxis

Timeline

• Start date: 2021-04-01
• Primary completion: 2021-04-01
• Completion: 2024-02-09
• First posted: 2021-04-01
• Last updated: 2021-04-01