NCT04823325

Determining the Presence of RAP in Orthognathic Patients and Its Effect on Root Resorption by Biomarkers

Use of Biomarkers in Early Surgery Patients to Determine Effectiveness of Regional Acceleratory Phenomenon and Its Effect on Root Resorption

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 13 (actual)
• Sponsor: Bezmialem Vakif University · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

A prospective clinical trial to what extent inflammatory biomarkers are affected by the medication after orthognathic surgery in early surgical cases and whether these biomarkers affects the amount of maxillary or mandibular incisor root resorption.

Detailed description

To conduct a prospective clinical trial to what extent inflammatory biomarkers such as OPG, RANKL, IL-1, IL-6, and CRP are affected by the medication after orthognathic surgery in early surgical cases and whether these biomarkers affects the amount of maxillary or mandibular incisor root resorption.

Conditions

• Class III Malocclusion
• Root Resorption

Interventions

Type	Name	Description
PROCEDURE	Orthognathic Surgery	The duration for presurgical orthodontic treatment was; 7,7 ± 1,7 months.

Timeline

• Start date: 2019-01-05
• Primary completion: 2021-01-01
• Completion: 2021-01-01
• First posted: 2021-03-30
• Last updated: 2021-03-30

Locations

1 site across 1 country: Turkey (Türkiye)