Trials / Completed
CompletedNCT04821323
A Study Exploring the Use of Challenge Agents in Healthy Volunteers - Intervention Specific Appendix
A Phase 0 Platform Study Exploring the Use of Challenge Agents in Healthy Volunteers
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 10 (actual)
- Sponsor
- Janssen Research & Development, LLC · Industry
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to characterize the disruption of intestinal barrier as a result of indomethacin challenge in healthy volunteers using an orally administered lactulose-mannitol test.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Indomethacin | Indomethacin capsules will be administered orally. |
| DIAGNOSTIC_TEST | Lactulose-mannitol | Lactulose-mannitol solution will be administered orally. |
Timeline
- Start date
- 2021-03-10
- Primary completion
- 2021-05-07
- Completion
- 2021-05-07
- First posted
- 2021-03-29
- Last updated
- 2021-06-25
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT04821323. Inclusion in this directory is not an endorsement.