Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT04821219

Personalized Management of Pancreatic Adenocarcinoma Using Patient-Derived Tumoroids

Establishing a Platform for Personalized Approach to the Management of Pancreatic Adenocarcinoma Using Patient-Derived Tumoroids

Status
Withdrawn
Phase
N/A
Study type
Interventional
Enrollment
0 (actual)
Sponsor
Mayo Clinic · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is designed to prospectively investigate the feasibility of establishing patient-derived tumoroids (PDT) as a platform for a personalized approach for response prediction and guide optimal neoadjuvant and/or adjuvant approach. PDT will be investigated to determine drug sensitivity, predict the response to chemotherapy agents and radiation therapy, and validate this response in treated patients, and to establish the feasibility of PDT as a platform for a personalized approach to guide multimodality treatment.

Conditions

Interventions

TypeNameDescription
OTHERTreatment prediction PDT platformPDT will be generated and response to various chemotherapies and radiation will be investigated. Actionable targets will be identified and response to the target drug will be assessed and compared to the conventional treatment options.

Timeline

Start date
2022-01-01
Primary completion
2023-12-31
Completion
2023-12-31
First posted
2021-03-29
Last updated
2022-02-24

Source: ClinicalTrials.gov record NCT04821219. Inclusion in this directory is not an endorsement.