NCT04820374

The Guiding Significance of Pupil Monitoring in the Perioperative Period

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Yangzhou University · Academic / Other
• Sex: All
• Age: 65 Years – 95 Years
• Healthy volunteers: Not accepted

Summary

The pupil diameter is affected by both sympathetic and parasympathetic nerves, and its latency and response amplitude mainly reflect the functional status of the parasympathetic nerve. Clinically, the diagnosis of neurological diseases can often be made based on changes in pupils. An appropriate depth of anesthesia can cause minimal damage to the body after surgery, thereby reducing the impact on brain function and cognitive function. The occurrence of postoperative delirium will have adverse effects on the prognosis of patients, such as prolonging the hospital stay, increasing the mortality of patients after surgery, and increasing early postoperative cognitive dysfunction.

Conditions

• Pupil Diameter
• Pupil Contraction Rate
• Pupil Light Reflection

Interventions

Type	Name	Description
PROCEDURE	pupil's light and pupil diameter	It is necessary to meet the requirement that the pupil's light reflection is slightly restored to the state of entering the room, and then the tube is extubated and the pupil diameter and the light reflection are restored to the state of entering the room, leaving the recovery room

Timeline

• Start date: 2020-11-01
• Primary completion: 2021-05-31
• Completion: 2021-06-30
• First posted: 2021-03-29
• Last updated: 2023-01-06

Locations

1 site across 1 country: China