NCT04818125

Circulating Cancer Cells/Macrophage HYbrid Cells in Patients With Breast Cancer.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 61 (actual)
• Sponsor: Institut Claudius Regaud · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Pilot, prospective, monocentric study aimed at evaluating the rate of patients with circulating cancer cell/macrophage hybrid cells in the peripheral blood. The study will be conducted on a population of patients with breast cancer (regardless of stage of the disease and the immunohistochemical subtype). For each included patient, blood samples will be taken and tumor specimens will be collected for the study. At the end of the blood collection, the patient will have completed his participation in the study.

Conditions

• Breast Cancer

Interventions

Type	Name	Description
OTHER	Patients with breast cancer (stage I, II III or IV)	Blood samples will be collected at different times: * at Baseline for all patients with breast cancer: before initiation of treatment (i.e. before initiation of planned treatment for stage I to III patients and before any new line of treatment for stage IV patients); * at the time of disease progression (or at 12 months in absence of progression) for patients with metastatic breast cancer (stage IV) For each patient a tumor sample from the initial diagnosis of the disease (i.e. primary tumor +/- biopsy of a metastasis) will be collected (archived tumor block) for the study.

Timeline

• Start date: 2021-03-31
• Primary completion: 2022-07-29
• Completion: 2022-07-29
• First posted: 2021-03-26
• Last updated: 2022-09-28

Locations

1 site across 1 country: France