NCT04817748

Metabolomics Characterization of Biomarkers of Different Types of Myocardial Infarction in Different Time.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: Shanghai 10th People's Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 76 Years
• Healthy volunteers: Accepted

Summary

To find new biomarkers through Metabonomics Study of different types of myocardial infarction in Different Time.

Detailed description

In recent years, with the deepening understanding of the mechanism of myocardial infarction, in addition to the early understanding of plaque rupture, plaque erosion and other mechanisms, studies have found that inflammation, immunity, metabolism and other factors also play an increasingly important role in the occurrence and development of myocardial infarction. The LoDoCo2 study published at the 2020 ESC annual meeting and the COLCOT study previously published confirmed for the first time the therapeutic effect of anti-inflammatory drug colchicine in chronic coronary disease and acute myocardial infarction. At the same time, the fourth international definition of myocardial infarction also defines three different types of acute ST segment elevation myocardial infarction (STEMI), acute non ST segment elevation myocardial infarction (NSTEMI) and non infarct acute myocardial infarction (MINOCA). However, there are no clear research results on the mechanism, especially the mechanism of MINOCA. Therefore, the study of acute myocardial infarction in three groups is of great significance.

Conditions

• Myocardial Infarction

Timeline

• Start date: 2020-11-17
• Primary completion: 2021-05-01
• Completion: 2021-05-01
• First posted: 2021-03-26
• Last updated: 2021-03-26

Locations

1 site across 1 country: China