Clinical Trials Directory

Trials / Unknown

UnknownNCT04817306

Pan-canceR Early DetectIon projeCT (PREDICT)

A Prospective, Multicenter Study on Development and Validation of the Performance of a cfDNA Methylation-based Model for Early Cancer Detection (Pan-canceR Early DetectIon projeCT, PREDICT Study)

Status
Unknown
Phase
Study type
Observational
Enrollment
14,026 (estimated)
Sponsor
Shanghai Zhongshan Hospital · Academic / Other
Sex
All
Age
40 Years – 75 Years
Healthy volunteers
Accepted

Summary

PREDICT is a prospective, multicenter study for the early detection of pan-cancer through cell-free DNA (cfDNA) methylation-based model, in which approximately 14,000 participants will be enrolled. The development and validation of the model will be conducted in participants with cancers or benign diseases, along with non-tumor (healthy) individuals through a two-stage approach. The sensitivity and specificity of the model in cancer early detection will be evaluated, and the accuracy of the identification for tissue of origin will be obtained.

Conditions

Interventions

TypeNameDescription
DEVICEMulti-cancer early detection testBlood collection and multi-cancer early detection testing

Timeline

Start date
2021-03-29
Primary completion
2022-12-31
Completion
2023-03-31
First posted
2021-03-26
Last updated
2021-03-30

Locations

3 sites across 1 country: China

Source: ClinicalTrials.gov record NCT04817306. Inclusion in this directory is not an endorsement.