Clinical Trials Directory

Trials / Terminated

TerminatedNCT04816916

Efficacy and Safety of AXA1665 in Cirrhotic Subjects With Prior Overt Hepatic Encephalopathy

A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of AXA1665 in Subjects With Liver Cirrhosis and Prior Overt Hepatic Encephalopathy (EMMPOWER)

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
12 (actual)
Sponsor
Axcella Health, Inc · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a global study to compare the effects of AXA1665, an orally active mixture of amino acids, compared to placebo, on cognitive and physical function, as well as the safety and tolerability of AXA1665.

Conditions

Interventions

TypeNameDescription
DRUGAXA1665AXA1665 administered TID with food
DRUGPlaceboMatching placebo administered TID with food

Timeline

Start date
2021-06-29
Primary completion
2022-06-30
Completion
2022-06-30
First posted
2021-03-25
Last updated
2022-07-27

Locations

40 sites across 7 countries: United States, Canada, Hungary, Italy, Poland, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT04816916. Inclusion in this directory is not an endorsement.