NCT04816253

Controlling Post-extraction Complications of Impacted Mandibular Third Molar

Methylprednisolone and Hyaluronic Acid Versus Each Agent Alone to Control Post-extraction Complications of Impacted Mandibular Third Molar

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: Al-Azhar University · Academic / Other
• Sex: All
• Age: 20 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Impacted mandibular 3rd molar will be extracted in all patients, then patients will be divided, according to material placed in extraction socket into 3 groups: control, hyaluronic acid and honey. Then post extraction complications will be evaluated

Detailed description

Impacted Mandibular third molar will be extracted under local anesthesia Through standard surgical flap elevation, after extraction and wound irrigation a material facilitate healing will be placed. According to material will be placed patients will be divide into 3 group: control ( no material, second group hyaluronic acid, third group ( honey).. then wound will be closed. Postoperative pain ( through visual analog scale) , edema, total dose of analgesic, mandibular movement (interincisal distance in mm) will be evaluated preoperative, 1,2,3,7, and 10 day after extraction

Conditions

• Preventing Postextraction Complication

Interventions

Type	Name	Description
DRUG	Normal saline	Normal saline irrigation and No other drug placed after extraction
DRUG	Hyaluronic acid	Immediately after removal of impacted tooth (hyaluronic acid) placed in extraction socket
DRUG	Methylprednisolone	Methylprednsolone will be injected half an hour preoperatively
DRUG	Methylprednisolone and Hyaluronic acid	Methylprednisolone will be injected half an hour preoperatively and Immediately after removal of impacted tooth (hyaluronic acid) placed in extraction socket

Timeline

• Start date: 2021-02-10
• Primary completion: 2021-06-20
• Completion: 2021-06-20
• First posted: 2021-03-25
• Last updated: 2021-07-22

Locations

1 site across 1 country: Saudi Arabia