NCT04813679

Bed-side Ultrasound in Neutropenic Enterocolitis

Bed-side Ultrasound in the Evaluation of Gastro-intestinal Tract and Neutropenic Enterocolitis (NEC) in Neutropenic Patients.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,740 (actual)
• Sponsor: Azienda Ospedaliero, Universitaria Pisana · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Neutropenic enterocolitis (NEC) is a life-threatening complication of leukemic and solid tumors patients (pts) treated with chemotherapy (CHT) with high mortality rate up to 50-100%. Perforation occurs in 5%-10% of cases. Early diagnosis is crucial to start conservative medical management (CMM), which appears the optimal strategy for most cases. NEC should be always suspected in Neutropenic pts with abdominal pain, fever and diarrhea. Ultrasound (US) can be used to evaluate bowel-wall thickening (BWT). The objective of this study is to evaluate prospectively if US can detect early signs of NEC and guide a prompt treatment (CMM or surgical) and thus reduce mortality.

Conditions

• Neutropenic Enterocolitis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Bed side Ultrasound Sonography	Bed side Ultrasound in Neutropenic patients within 12 h from onset of any symptom such as fever and/or abdominal pain and/or diarreha

Timeline

• Start date: 2007-03-01
• Primary completion: 2018-01-01
• Completion: 2018-01-01
• First posted: 2021-03-24
• Last updated: 2021-03-24

Locations

1 site across 1 country: Italy