Trials / Unknown
UnknownNCT04810234
Neural Correlates of tVNS
Functional Neural Correlates of Transcutaneous Vagal Nerve Stimulation: Effects of Anatomical Site and Waveform Parameters - An Exploratory High Resolution fMRI Study in Healthy Volunteers
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 16 (estimated)
- Sponsor
- Maastricht University Medical Center · Academic / Other
- Sex
- Female
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
Transcutaneous vagal nerve stimulation (tVNS) has been applied to a number of disease areas including visceral pain, depression, cluster headache and Alzheimer's disease. However, there is marked heterogeneity in these studies pertaining to i) the anatomical site of stimulation (neck, inner concha or tragus of ear), and ii) the waveform parameters of the stimulating impulse. This exploratory cross-sectional study will address these knowledge gaps by comparative functional neuroimaging of the neural correlates of tVNS with disparate anatomical sites and electrical waveform characteristics during rest in healthy participants.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | transcutaneous vagal nerve stimulation (tVNS) | Cervical and auricular transcutaneous stimulation of the vagus nerve |
Timeline
- Start date
- 2020-11-01
- Primary completion
- 2021-06-01
- Completion
- 2021-06-01
- First posted
- 2021-03-22
- Last updated
- 2021-03-22
Locations
2 sites across 2 countries: Netherlands, United Kingdom
Source: ClinicalTrials.gov record NCT04810234. Inclusion in this directory is not an endorsement.