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UnknownNCT04809454

Frequency of Florid Hyperthyroidism In Patients Taking Iodinated Salt

Frequency of Florid Hyperthyroidism In Patients Taking Iodinated Salt: A Cross Sectional Study

Status
Unknown
Phase
Study type
Observational
Enrollment
100 (estimated)
Sponsor
Services Institute of Medical Sciences, Pakistan · Other Government
Sex
All
Age
18 Years – 60 Years
Healthy volunteers

Summary

Thyroxin a vital hormone for life lot of body functions depend on proper functioning on pituitary thyroid axis. it exists in two major forms Thyroxine (T4) and (T3) , each of them containing two iodine atoms on their inner (tyrosine) ring. Synthesis of reasonable quantities of thyroid hormones requires adequate iodine intake to allow sufficient thyroidal uptake. The World Health Organization (WHO) recommendation for daily intake of iodine is 150 μg for children ≥12 years and adults, and 250 μg for pregnant and lactating women. However as we know optimum amount of iodine is required for normal pituitary thyroid axis like wise excessive intake may cause over functioning of axis hence over production of hormone that can be manifested both clinically and biochemically. This study is designed to observe the frequency of over hyperthyroidism in patients taking iodinated salt.

Detailed description

All patients presenting to endocrine clinic fulfilling inclusion and exclusion criteria will be recruited. They will be examined, their vitals including blood pressure pulse will be noted, thyroid clinical examination including eye signs and thyroid status will be done biochemical Thyroid profile (TSH, Free T3 \& Free T4) will be noted in predesigned proforma. Statistical Analysis will be done ,after data is entered in Statistical Package for the Social Sciences (SPSS) version 25 .qualitative data will be presented as frequencies and percentages while quantitative data will be presented as mean medians and standard deviations.

Conditions

Timeline

Start date
2021-10-01
Primary completion
2022-03-01
Completion
2022-03-01
First posted
2021-03-22
Last updated
2021-09-22

Locations

1 site across 1 country: Pakistan

Source: ClinicalTrials.gov record NCT04809454. Inclusion in this directory is not an endorsement.