NCT04808856

Treatment of Refractory Gout With ACTH or Methylprednisolone

Treatment of Refractory Gout With Adrenocorticotropic Hormone or Methylprednisolone

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Shanghai 10th People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To clarify the therapeutic effect and safety evaluation of ACTH in refractory gouty arthritis and special population, and to explore its mechanism of action.

Detailed description

When patients with acute gout have multiple comorbidities and complications , traditional treatment methods are often contraindicated . From the current clinical research evidence , we have seen the non-inferior effect of ACTH on glucocorticoids and non-steroidal anti-inflammatory drugs in the treatment of acute gout , as well as the good safety and extensive anti-inflammatory effect in addition to efficacy . Therefore , we designed this study to update and improve the treatment of acute gout attacks , and to try to clarify the mechanism of action .

Conditions

• Gout

Interventions

Type	Name	Description
DRUG	Adrenocorticotropic Hormone	Adrenocorticotropic Hormone Injection 25u qd iv \*3d
DRUG	Methylprednisolone Injection	Methylprednisolone Injection 40mg qd iv \*3d

Timeline

• Start date: 2021-04-01
• Primary completion: 2022-04-01
• Completion: 2022-04-01
• First posted: 2021-03-22
• Last updated: 2021-03-22

Locations

1 site across 1 country: China