NCT04805866

Tracking Neural Synergies After Stroke.

Tracking Neural Synergies During Gait Rehabilitation After Stroke

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 36 (actual)
• Sponsor: Shirley Ryan AbilityLab · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to identify neural muscle synergies of patients post-stroke and track them during an inpatient acute rehabilitation. To this end, the researchers will use an innovative approach based on the identification of large populations of motor units from recordings of surface high-density electromyography (HD-EMG).

Detailed description

The researchers will focus on the identification of neural muscle synergies of leg and thigh muscles during postural and locomotor tasks in patients post stroke. To this end, the researchers will recruit 20 patients participating in inpatient rehabilitation at Shirley Ryan AbilityLab in the early subacute phase after stroke and 20 age-matched healthy controls. The researchers will ask them to perform postural tasks and walking trials at their preferential speed. All assessments will be performed by a licensed physiotherapist as per the standard of care once a week during three weeks of inpatient rehabilitation at the Shirley Ryan AbilityLab. During these tasks, the researchers will record HD-EMG signals from four muscle groups (Quadriceps, Hamstrings, Triceps Surae, Tibialis anterior).

Conditions

• Stroke

Timeline

• Start date: 2021-06-09
• Primary completion: 2024-02-21
• Completion: 2025-07-31
• First posted: 2021-03-18
• Last updated: 2025-05-25

Locations

1 site across 1 country: United States