NCT04805385

Effects of Lactobacillus Plantarum PS128 in Patients With Tourette's Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 121 (actual)
• Sponsor: China Medical University Hospital · Academic / Other
• Sex: All
• Age: 4 Years – 18 Years
• Healthy volunteers: Accepted

Summary

To evaluate whether supplementing with PS128 can improve the symptoms and quality of life related to Tourette's disease in children.

Detailed description

This is a randomized double-blind healthy control study and the implementation period is after Institutional Review Board (IRB) approval to December 31, 2023. Experimental group: 80 subjects who meet the criteria for the admission of Tourette's disease will be enrolled. They will consume the PS128 or placebo capsules every day, 2 capsules at a time, for 12 weeks. Healthy control group: 40 subjects of the same age as the experimental group will be included, without any intervention measures, only collect stool sample once.

Conditions

• Tourette's Syndrome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	PS128	Each PS128 capsule contained \>1 × 10\^10 colony forming units (CFU) with microcrystalline cellulose and weights 425 ± 25 mg The placebo capsules only contained 425 ± 25 mg microcrystalline cellulose

Timeline

• Start date: 2021-11-29
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2021-03-18
• Last updated: 2026-01-29

Locations

1 site across 1 country: Taiwan