NCT04804657

Effects of Sage Extracts on Cognitive Function During Aerobic Exercise

Effects of Sage Extracts on Cognitive Function During Aerobic Exercise in Healthy Individuals

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 17 (actual)
• Sponsor: University of Burgundy · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Extracts of sage have been reported to interact with central nervous system (CNS) mechanisms relevant to cognitive performance but, to date, no trial has clearly demonstrated the possible effects in healthy individuals in fatiguing conditions. The current study investigates the effects of this supplementation in healthy males and females versus placebo on cognition, heart rate and perceived exertion, during a fatiguing cycling exercise.

Detailed description

Healthy males and females will be tested in fresh and fatiguing conditions to mimic individuals at the beginning or during a competition where cognitive function are important for decision making for example. Tests will be conducted during the warm-up (fresh), during fatiguing situations (during two consecutive 10-minutes pedaling exercises) and during recovery. Tests will include a reverse digit memory test (from 3 to 7 digits), a stroop test, a simple reaction time test. Moreover, heart rate and rating of perceived exertion will be quantified.

Conditions

• Healthy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Sage extracts Cognivia	Cognivia is composed of 400 mg of aqueous extract from Salvia officinalis and the remaining 200 mg contained 50 µL of Salvia lavandulaefolia essential oil and encapsulated with gum acacia. It will be administrated the the morning before the endurance test (oral administration).
DIETARY_SUPPLEMENT	Placebo	Made with maltodextrin. It will be administrated the the morning before the endurance test (oral administration).

Timeline

• Start date: 2021-02-01
• Primary completion: 2021-02-28
• Completion: 2021-03-15
• First posted: 2021-03-18
• Last updated: 2021-03-18

Locations

1 site across 1 country: France