NCT04803500

Simvastatin Around Immediate Implant

Restoration of Immediate Peri-implant Defect by Simvastatin: a Controlled Clinical and Cone Beam Computed Tomography Study

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: 20 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The study evaluated the effect of local application of simvastatin around immediate implant on the amount of gap fill, ridge dimensional alterations and bone density in humans.

Conditions

• Immediate Implant Placement
• Bone Regeneration
• Alveolar Bone Resorption

Interventions

Type	Name	Description
DRUG	Simvastatin	single injection of simvastatin gel in the gap around immediately placed implant
DRUG	Placebo	single injection of the solid lipid nanoparticle carrier in the gap around immediately placed implant

Timeline

• Start date: 2015-04-02
• Primary completion: 2016-02-15
• Completion: 2016-05-03
• First posted: 2021-03-17
• Last updated: 2021-03-17