NCT04799509

Assessment of the 90-day Mortality Risk Score After VATS Lobectomy

Assessment of the 90-day Mortality Risk Score After Video-assisted Thoracoscopic Lobectomy in the Italian VATS Group Cohort

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 2,209 (actual)
• Sponsor: Università degli Studi dell'Insubria · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

A five classes (A-E) aggregate risk score predicting 90-day mortality after video-assisted thoracoscopic lobectomy for lung cancer, including as independent factors male sex (3 points), carbon monoxide lung diffusion capacity \<60% (1 point) and operative time \>150 minutes (1 point), has been recently published. This study aims to assess the effectiveness and reliability of this risk model in a large, independent cohort of patients, in order to confirm its generalizability.

Detailed description

From the Italian VATS Group Database, we selected patients who underwent video-assisted thoracoscopic lobectomy for non-small cell lung cancer. We calculated the aggregate risk score and the corresponding class of 90-day mortality risk for each patient. The correlation between risk classes and mortality rates was tested by Spearman's rho-test. Model calibration was evaluated by Hosmer-Lemeshow goodness-of-fit test.

Conditions

• Lung Cancer
• Surgery--Complications
• Morality

Interventions

Type	Name	Description
PROCEDURE	VATS lobectomy	VATS lobectomy

Timeline

• Start date: 2014-01-01
• Primary completion: 2018-11-27
• Completion: 2018-11-27
• First posted: 2021-03-16
• Last updated: 2021-03-22