NCT04794153

Investigating the Consumption of Different Protein Rich Whole Food Sources on Muscle Growth in Trained Males and Females

Assessing the Muscle Protein Synthetic Response Following the Ingestion of a Variety of Protein Rich Whole Foods Compared to an Isolated Protein Source.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: University of Exeter · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Background To date, most of the literature investigating the role of dietary protein in muscle growth has focused on isolated protein sources. However, dietary protein is most commonly consumed within a whole food source. Consuming dietary protein within a whole food matrix may additionally stimulate muscle growth. The idea being, there may be other components within food, capable of producing a greater response. Objectives: To assess the effect of consuming a variety of whole food sources, on the stimulation of muscle growth compared to an isolated protein source following a single bout of lower body resistance exercise. Methods Young healthy resistance-trained volunteers will consume a protein rich whole food source, following a bout of lower body resistance exercise. Stable isotope IV infusions and repeated blood and muscle samples will be taken to assess protein digestion and absorption, as well as muscle protein synthesis rates. Value of Research: To determine whether whole food sources potentiate muscle protein synthesis rates (and to what extent across whole food sources) compared to an isolated protein source. In doing so, we can further investigate the nutrients involved that may be contributing to this effect.

Conditions

• Nutritional Intervention Using Protein Rich Whole Food Sources

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	whole food sources	Foods selected are naturally high in protein and consumed by the general population as part of a meal.

Timeline

• Start date: 2021-05-01
• Primary completion: 2024-04-01
• Completion: 2024-05-01
• First posted: 2021-03-11
• Last updated: 2024-05-09

Locations

1 site across 1 country: United Kingdom