NCT04793256

Clinical and Cost-effectiveness of Fluoride Varnish Versus Resin Based Sealant (Part 2)

Clinical and Cost-effectiveness of Fluoride Varnish Versus Resin Based Sealant in Newly Erupted Permanent Molars in Group of Egyptian Children: A Randomized Clinical Trial(Part 2).

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 91 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 6 Years – 12 Years
• Healthy volunteers: Accepted

Summary

The aim of the present study is determine the cost-effectiveness, clinical- effectiveness, acceptability and adverse effect of resin sealants versus the fluoride varnish for the prevention of dental caries on newly erupted permanent molars.

Detailed description

A Cochrane systematic reviews found low quality evidence supporting Current practice guidelines that recommend the use of Resin based fissure sealant over Fluoride varnish in prevent dental caries. However, they did not address the cost-effectiveness, A more recent systematic review and meta-analysis concluded that no statistical significance difference between Resin based fissure sealant and Fluoride varnish with a high-quality evidence in prevent dental caries. This trial will measure cost effectiveness and clinical effectiveness for resin fissure sealant and fluoride varnish.

Conditions

• Cost Effectiveness

Interventions

Type	Name	Description
DEVICE	Fluoride varnish (3M Clinpro White Varnish 5% sodium fluoride).	5% sodium fluoride Varnish is a fluoride varnish which is applied to tooth surfaces
DEVICE	Resin based fissure sealant (3M Clinpro Sealant)	teeth will be isolated with cotton rolls and saliva ejector than etching for pits and fissure sealant

Timeline

• Start date: 2021-04-01
• Primary completion: 2022-05-01
• Completion: 2022-05-01
• First posted: 2021-03-11
• Last updated: 2021-03-11