Clinical Trials Directory

Trials / Unknown

UnknownNCT04792749

Clinical Effects of Metformin on Fertility-sparing Treatment for Early Endometrial Cancer

Status
Unknown
Phase
Phase 3
Study type
Interventional
Enrollment
77 (estimated)
Sponsor
Samsung Medical Center · Academic / Other
Sex
Female
Age
18 Years – 45 Years
Healthy volunteers
Accepted

Summary

The purpose of the study is to investigate the effects of metformin in addition to the conventional progestin therapy in the fertility-sparing treatment of early stage endometrial cancer.

Conditions

Interventions

TypeNameDescription
DRUGMetforminPatients are given 750, 1500, and 2000 mgs of metformin per os daily (dose increases weekly, then maintain at 2000 mgs) in addition to 500 mgs of medroxyprogesterone acetate per os daily and levonorgestrel-releasing intrauterine device for the treatment of early stage endometrial cancer.

Timeline

Start date
2021-06-01
Primary completion
2023-12-31
Completion
2024-03-31
First posted
2021-03-11
Last updated
2023-04-13

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT04792749. Inclusion in this directory is not an endorsement.