Trials / Completed
CompletedNCT04791995
Resuscitation and Capillary Reperfusion
REsuscitation and CAPillary rePerfusion - A Cohort Study With Prospective Inclusion
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 50 (actual)
- Sponsor
- Medical University of Vienna · Academic / Other
- Sex
- All
- Age
- 18 Years – 95 Years
- Healthy volunteers
- Not accepted
Summary
Persistent microperfusion alterations after return of spontaneous circulation (ROSC) are associated with poor survival. To our knowledge, no human studies evaluating microperfusion during cardiopulmonary resuscitation (CPR) with simple and pre-hospital available tests have been published. Capillary refill time (CRT) and skin-mottling-score (SMS) are parameters for microperfusion and evaluated in septic and cardiogenic shock. In animal studies, microperfusion was impaired during cardiac arrest, although not correlating with systemic blood pressure. The aim of this study is to investigate the correlation between impaired microcirculation (as measured with CRT and SMS) during resuscitation and ROSC resp. neurological outcome. Our clinical impression in daily routine is, that the appearance of a patient undergoing CPR is often linked to the outcome. We hypothesize, that this is due to changes in microperfusion of the skin.
Conditions
- Cardiac Arrest
- Cardiac Arrest, Out-Of-Hospital
- Cardiopulmonary Arrest
- Cardiopulmonary Arrest With Successful Resuscitation
Timeline
- Start date
- 2021-03-03
- Primary completion
- 2022-03-31
- Completion
- 2022-05-01
- First posted
- 2021-03-10
- Last updated
- 2022-09-26
Locations
1 site across 1 country: Austria
Source: ClinicalTrials.gov record NCT04791995. Inclusion in this directory is not an endorsement.