NCT04791098

Impact of Infectious Diseases Consultation on Vaccination Coverage Among People Waiting for a Kidney Transplant at the Clermont-Ferrand Hospital

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: University Hospital, Clermont-Ferrand · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Solid-organ transplant patients are at increased risk of infectious diseases. Among this population, infectious diseases may be life-threatening or lead to graft rejection. Their prevention is an important challenge. Despite specific national recommendations, vaccination is underutilized. That is why we propose a dedicated infectious diseases consultation during pre-kidney transplantation assessment.

Detailed description

The main objective of this study is to impove vaccine coverage before kidney transplantation. Enrollment was based on the waiting list for a kidney transplant. Patients newly listed are invited to participate by the transplant team (nephrology department) ; for those that are already registered, a notification letter is sent to their home. All patients included must : * complete a health questionnaire * take a blood test at day 0 : viral, bacterial and parasitic serologies, QuantiFERON-TB * take a chest X-ray and dental panoramic Patients randomized in interventional group will be seen in specific infectious diseases consultation at Clermont Ferrand Hospital. A letter of recommendations is sent to nephrologist for patients randomized in group control. The primary study endpoint (immunization coverage) is evaluated at 6 months.

Conditions

• Kidney Transplantation

Interventions

Type	Name	Description
OTHER	Specific infectious diseases consultation	Specific infectious diseases consultation at Clermont Ferrand Hospital with a specialist doctor : * Update vaccinations * Advice to travelers * Diagnostic and treatment of latent tuberculosis infection

Timeline

• Start date: 2020-09-16
• Primary completion: 2022-03-01
• Completion: 2026-04-01
• First posted: 2021-03-10
• Last updated: 2021-03-10

Locations

1 site across 1 country: France