NCT04788199

Novel Technique in Closure of Mesenteric Defects After Laparoscopic Roux-en-Y Gastric Bypass and Its Effect on Internal Hernia: a Case-control Study

Analytical Study of Internal Hernia Following Laparoscopic Roux-eny Gastric Bypass

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 928 (actual)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

This study is to investigate the rate of internal hernia after laparoscopic Rox-en-Y gastric bypass when the defects are closed using cyano-acrylate glue.

Detailed description

Background Internal hernia complicated by bowel obstruction is a well-recognized complication of laparoscopic Roux-en-Y gastric bypass (LRYGB). The present study aims to investigate the role of cyanoacrylate glue in the prevention of internal hernia (IH) after LRYGB and compare it with the open technique of managing mesenteric defects by leaving the mesentery intact without closure of mesenteric defects. Data from six UK hospitals have been involved in this study. Operations were done under the supervision of a single senior consultant surgeon of bariatric surgery. Methods The prospectively collected data of 813 patients with morbid obesity who underwent LRYGB were retrospectively analyzed. Patients were subdivided into two groups: group I comprising 185 patients who had the mesenteric defects closed with cyanoacrylate glue and group II comprising 628 patients who were managed by the open technique of leaving the mesentery intact without closure of the mesenteric defects.

Conditions

• Bariatric Surgery

Interventions

Type	Name	Description
OTHER	Closure of mesenteric defects using glue	Cyano-acrylate glue is a glue known to be used in surgery as tissue adhesive.

Timeline

• Start date: 2018-06-15
• Primary completion: 2020-01-31
• Completion: 2020-01-31
• First posted: 2021-03-09
• Last updated: 2021-03-09

Locations

1 site across 1 country: United Kingdom