NCT04788069

Effect of Sourdough Breads Consumption on Postprandial Responses, Satiety and Food Intake at Subsequent Meal

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 43 (actual)
• Sponsor: KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

During this project the effect of different types of sourdough breads consumption on satiety, energy intake at subsequent meal and postprandial metabolic responses, will be investigated.

Detailed description

A 3-phase randomised cross-over trial will be applied consisting of 3 intervention periods of 2 weeks, with a test day performed at the last day of each intervention period. During each intervention period, participants will consume a fixed amount of test bread, replacing their regular bread, and they will keep food and stool diaries preceding each Test-day. Faecal samples will be collected before each Test-day. On the Test-day, participants will perform a gastric emptying breath test. Furthermore, blood samples and appetite ratings will be collected at regular time points after consumption of the test bread for measurement of glucose, insulin, gut peptides, short-chain fatty acids (SCFA) and blood lipids. Food intake will be assessed by offering the subjects a standard lunch to be consumed ad-libitum.

Conditions

• Energy Intake
• Appetite Regulation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Wholemeal bread	180g wholemeal bread/day + fixed portion at test day
DIETARY_SUPPLEMENT	Sourdough bread	180g sourdough bread/day + fixed portion at test day
DIETARY_SUPPLEMENT	Bread with sourdough	180g bread with sourdough/day + fixed portion at test day

Timeline

• Start date: 2021-06-01
• Primary completion: 2024-02-05
• Completion: 2024-02-05
• First posted: 2021-03-09
• Last updated: 2024-05-14

Locations

1 site across 1 country: Belgium