Clinical Trials Directory

Trials / Completed

CompletedNCT04787211

A Study of Human Monoclonal Antibodies, BRII-196 and BRII-198

A Phase 2 Study to Evaluate the Safety and Efficacy of Human Monoclonal Antibodies, BRII-196 and BRII-198, Administered by Intravenous Infusion for the Treatment of COVID-19 Patients

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
48 (actual)
Sponsor
Brii Biosciences Limited · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The aim of this phase 2 study is to evaluate the safety and efficacy of single dose IV infusion of BRII-196 and BRII-198 given as combination therapy in patients with severe COVID-19, and mild to moderate COVID-19 and asymptomatic carrier.

Conditions

Interventions

TypeNameDescription
DRUGBRII-196 and BRII-198BRII-196 and BRII-198 given by intravenous administration
DRUGPlaceboPlacebo given by intravenous administration

Timeline

Start date
2021-06-20
Primary completion
2021-12-02
Completion
2021-12-02
First posted
2021-03-08
Last updated
2023-03-03

Locations

6 sites across 1 country: China

Source: ClinicalTrials.gov record NCT04787211. Inclusion in this directory is not an endorsement.