NCT04786470

Transversus Abdominis Plane Catheter Following Kidney Transplantation

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Western University, Canada · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Continuous Infusion of Local Anesthetic After Kidney Transplantation This is a phase III, randomized, double-blinded, sham-controlled trial comparing the use of a continuous infusion of local anesthetic via transversus abdominis plane (TAP) catheter to a saline infusion (sham) via TAP catheter along with standard postoperative analgesia in patients undergoing kidney transplantation. Patients will have a TAP catheter placed at the time of kidney transplantation by the surgical team under direct vision. They are then randomized to a continuous infusion of local anesthetic or saline for 48 hours postoperatively. Both groups will receive a standard postoperative analgesic regimen including a Patient Controlled Analgesic (PCA) pump and multimodal analgesics including acetaminophen and gabapentin.

Conditions

• Pain, Postoperative
• Kidney Transplant

Interventions

Type	Name	Description
DRUG	Ropivacaine	Ropivacaine infusion via transversus abdominis plane catheter.
DRUG	Saline	Saline infusion via transversus abdominis plane catheter.

Timeline

• Start date: 2021-05-01
• Primary completion: 2022-11-01
• Completion: 2022-11-01
• First posted: 2021-03-08
• Last updated: 2021-03-08

Regulatory

• FDA-regulated drug study