NCT04786379

Surgical Management of Knee Septic Arthritis

Open vs Arthroscopic Treatment of Septic Arthritis in the Adult Native Knee: A Prospective Trial

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Texas Tech University Health Sciences Center, El Paso · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Surgical excisional debridement is the mainstay of management in septic arthritis with necessary decompression, lavage, debridement, and partial synovectomy. However, there has been considerable debate over the optimal modality. Most surgeons perform an open arthrotomy or arthroscopic debridement, although serial aspiration can be considered as an option in very limited circumstances with patients who cannot tolerate surgery. While open arthrotomy has been often utilized, there has been an increasing number of proponents for arthroscopic treatment citing lower re-infection rates and better functional outcomes. However, there has been a lack of well-designed prospective studies comparing surgical treatment modalities for native knee septic arthritis. The goals of this present study are to determine if arthroscopic management of septic arthritis in the native knee resulted in a lower number of surgeries and a shorter length of stay compared to open arthrotomy. Secondary outcomes included differences in postoperative pain and improvements in Lysholm knee scores.

Conditions

• Septic Arthritis

Interventions

Type	Name	Description
PROCEDURE	Arthroscopic Irrigation and Debridement	Patients with confirmed septic arthritis treated with multiple small incisions to perform irrigation and debridement with partial synovectomy.
PROCEDURE	Open Arthrotomy with irrigation and debridement	Patients with confirmed septic arthritis treated with a single large incision, open arthrotomy to perform irrigation and debridement with partial synovectomy.

Timeline

• Start date: 2021-04-01
• Primary completion: 2022-04-30
• Completion: 2022-04-30
• First posted: 2021-03-08
• Last updated: 2023-12-08

Locations

1 site across 1 country: United States