NCT04780802

Balloon Assisted Transarterial Therapy for Hepatocellular Carcinoma

Balloon Assisted Transarterial Therapy for Hepatocellular Carcinoma: a Study on the Proof of Treatment Concept and Exploration of Selection Criteria for Clinical Application

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To prove the treatment concept of the use of balloon assistance in transarterial therapy for HCC.

Detailed description

Transcatheter arterial chemoembolization (TACE) has been playing an important role in the treatment algorithm for patients with multifocal or large intrahepatic lesions of hepatocellular carcinoma (HCC) not eligible for surgical resection, transplantation, or local ablative therapy. The use of balloon assisted TACE has been proposed recently and it could be one of the possible ways to improve the effectiveness of drug delivery to the target tumor and therefore leading to improved treatment outcome.

Conditions

• Hepatocellular Carcinoma

Interventions

Type	Name	Description
PROCEDURE	The balloon catheter is placed at the various arterial feeders of the tumor	use of a balloon catheter for providing balloon occlusion, in addition to the standard microcatheter for drug delivery, both catheters are to be placed in parallel through a single guide catheter. Only one arterial puncture wound is involved. The inflated balloon provides temporary occlusion of all arterial tumor feeders except for the one which is selectively catheterized with a microcatheter for delivery of the therapeutic agent. The therapeutic agent consists of Lipiodol mixed with a chemotherapeutic drug, it is delivered through the microcatheter under fluoroscopic control.

Timeline

• Start date: 2022-05-01
• Primary completion: 2022-09-30
• Completion: 2022-09-30
• First posted: 2021-03-04
• Last updated: 2022-10-21

Locations

1 site across 1 country: Hong Kong