Trials / Terminated
TerminatedNCT04780581
Glucocorticoid Therapy in Coronavirus Disease COVID-19 Patients
MP3-pulses-COVID-19. Methylprednisolone Pulses Versus Dexamethasone According RECOVERY Protocol in Patients With Pneumonia Due to SARS-COV-2 Coronavirus Infection
- Status
- Terminated
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 128 (actual)
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Treatment with glucocorticoids in COVID patients. Low-intervention, phase IV, open-label, randomised, low-intervention clinical trial comparing 2 active treatments.
Detailed description
The use of high-dose bolus glucocorticoids in the treatment of patients with COVID-19 infection will increase the anti-inflammatory effect without increasing side effects. This will allow a better patient outcome, reducing the number of deaths and the need for intubation or admission to the Intensive Care Unit.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Dexamethasone | 6 mg/24h - 10 days |
| DRUG | Methylprednisolone | 250 mg/ 24h - 3 days |
Timeline
- Start date
- 2021-02-01
- Primary completion
- 2021-11-09
- Completion
- 2021-11-09
- First posted
- 2021-03-03
- Last updated
- 2025-01-06
- Results posted
- 2025-01-06
Locations
4 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT04780581. Inclusion in this directory is not an endorsement.